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CRANAD-28: A Robust Fluorescent Compound for Visualization of Amyloid Beta Plaques

CRANAD-28, a difluoroboron curcumin analogue, has been demonstrated in earlier reports to successfully label amyloid beta (Aβ) plaques for imaging both ex vivo and in vivo. CRANAD-28’s imaging brightness, ability to penetrate the blood brain barrier, and low toxicity make the compound a potentially...

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Detalles Bibliográficos
Autores principales: Ran, Kathleen, Yang, Jing, Nair, Anil V., Zhu, Biyue, Ran, Chongzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070309/
https://www.ncbi.nlm.nih.gov/pubmed/32079064
http://dx.doi.org/10.3390/molecules25040863