Revisiting the Radiosynthesis of [(18)F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease

[(18)F]FPEB is a positron emission tomography (PET) radiopharmaceutical used for imaging the abundance and distribution of mGluR5 in the central nervous system (CNS). Efficient radiolabeling of the aromatic ring of [(18)F]FPEB has been an ongoing challenge. Herein, five metal-free precursors for the...

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Detalles Bibliográficos
Autores principales: Varlow, Cassis, Murrell, Emily, Holland, Jason P., Kassenbrock, Alina, Shannon, Whitney, Liang, Steven H., Vasdev, Neil, Stephenson, Nickeisha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070414/
https://www.ncbi.nlm.nih.gov/pubmed/32098347
http://dx.doi.org/10.3390/molecules25040982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070414/
https://www.ncbi.nlm.nih.gov/pubmed/32098347
http://dx.doi.org/10.3390/molecules25040982

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