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Coixol Suppresses NF-κB, MAPK Pathways and NLRP3 Inflammasome Activation in Lipopolysaccharide-Induced RAW 264.7 Cells

Coixol, a plant polyphenol extracted from coix (Coix lachryma-jobi L.var.ma-yuen Stapf), has not been investigated for its anti-inflammatory effect. In this study, using a lipopolysaccharide (LPS)-induced macrophage cell model, we observed that coixol can effectively reduce the expression of interle...

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Detalles Bibliográficos
Autores principales: Hu, Yusheng, Zhou, Qilyu, Liu, Tianlong, Liu, Zhongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070437/
https://www.ncbi.nlm.nih.gov/pubmed/32085388
http://dx.doi.org/10.3390/molecules25040894