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New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets

Several anti-inflammatory agents based on pyrazole and imidazopyrazole scaffolds and a large library of substituted catechol PDE4D inhibitors were reported by us in the recent past. To obtain new molecules potentially able to act on different targets involved in inflammation onset we designed and sy...

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Detalles Bibliográficos
Autores principales: Brullo, Chiara, Massa, Matteo, Rapetti, Federica, Alfei, Silvana, Bertolotto, Maria B., Montecucco, Fabrizio, Signorello, Maria Grazia, Bruno, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070443/
https://www.ncbi.nlm.nih.gov/pubmed/32085423
http://dx.doi.org/10.3390/molecules25040899