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Allosteric GABA(A) Receptor Modulators—A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility †

GABA(A) receptor modulators are structurally almost as diverse as their target protein. A plethora of heterocyclic scaffolds has been described as modulating this extremely important receptor family. Some made it into clinical trials and, even on the market, some were dismissed. This review focuses...

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Detalles Bibliográficos
Autores principales: Vega Alanis, Blanca Angelica, Iorio, Maria Teresa, Silva, Luca L., Bampali, Konstantina, Ernst, Margot, Schnürch, Michael, Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070463/
https://www.ncbi.nlm.nih.gov/pubmed/32102309
http://dx.doi.org/10.3390/molecules25040999