Betulinic Acid-Nitrogen Heterocyclic Derivatives: Design, Synthesis, and Antitumor Evaluation in Vitro

Betulinic acid (BA) is a star member of the pentacyclic triterpenoid family, which exhibits great prospects for antitumor drug development. In an attempt to develop novel antitumor candidates, 21 BA-nitrogen heterocyclic derivatives were synthetized, in addition to four intermediates, 23 of which we...

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Detalles Bibliográficos
Autores principales: Yang, Yuqin, Xie, Tianxin, Tian, Xuehao, Han, Nana, Liu, Xiaojing, Chen, Hongshan, Qi, Jinchai, Gao, Feng, Li, Wen, Wu, Qianwen, Huo, Su, Gu, Yuhao, Dai, Ziqi, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070564/
https://www.ncbi.nlm.nih.gov/pubmed/32093264
http://dx.doi.org/10.3390/molecules25040948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070564/
https://www.ncbi.nlm.nih.gov/pubmed/32093264
http://dx.doi.org/10.3390/molecules25040948

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