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Biological Activity Profiles of Multitarget Ligands from X-ray Structures
In pharmaceutical research, compounds with multitarget activity receive increasing attention. Such promiscuous chemical entities are prime candidates for polypharmacology, but also prone to causing undesired side effects. In addition, understanding the molecular basis and magnitude of multitarget ac...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070578/ https://www.ncbi.nlm.nih.gov/pubmed/32059498 http://dx.doi.org/10.3390/molecules25040794 |