Synthesis and In Vitro Anticancer Evaluation of Novel Chrysin and 7-Aminochrysin Derivatives

Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position 7. A novel method was developed for the preparation of 7-aminochrysin derivatives via the Smiles rearrangemen...

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Detalles Bibliográficos
Autores principales: Mayer, Szabolcs, Keglevich, Péter, Ábrányi-Balogh, Péter, Szigetvári, Áron, Dékány, Miklós, Szántay, Csaba, Hazai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070641/
https://www.ncbi.nlm.nih.gov/pubmed/32079315
http://dx.doi.org/10.3390/molecules25040888