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A Novel Assay Method to Determine the β-Elimination of Se-Methylselenocysteine to Monomethylselenol by Kynurenine Aminotransferase 1

Kynurenine aminotransferase 1 (KYAT1 or CCBL1) plays a major role in Se-methylselenocysteine (MSC) metabolism. It is a bi-functional enzyme that catalyzes transamination and beta-elimination activity with a single substrate. KYAT1 produces methylselenol (CH(3)SeH) via β-elimination activities with M...

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Detalles Bibliográficos
Autores principales: Selvam, Arun Kumar, Björnstedt, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070735/
https://www.ncbi.nlm.nih.gov/pubmed/32033380
http://dx.doi.org/10.3390/antiox9020139