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Amino Acid-Linked Low Molecular Weight Polyethylenimine for Improved Gene Delivery and Biocompatibility

The construction of efficient and low toxic non-viral gene delivery vectors is of great significance for gene therapy. Herein, two novel polycations were constructed via Michael addition from low molecular weight polyethylenimine (PEI) 600 Da and amino acid-containing linkages. Lysine and histidine...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Ru, Zhang, Ji, Zhang, Ju-Hui, Xiao, Ya-Ping, He, Xi, Liu, Yan-Hong, Yu, Xiao-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070781/
https://www.ncbi.nlm.nih.gov/pubmed/32098282
http://dx.doi.org/10.3390/molecules25040975