Using Real‐World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic‐Pharmacodynamic Study

Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real‐world psoriasis data were used to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for the first‐line therapeutic antibody ustekinumab. The impact of di...

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Detalles Bibliográficos
Autores principales: Pan, Shan, Tsakok, Teresa, Dand, Nick, Lonsdale, Dagan O., Loeff, Floris C., Bloem, Karien, de Vries, Annick, Baudry, David, Duckworth, Michael, Mahil, Satveer, Pushpa‐Rajah, Angela, Russell, Alice, Alsharqi, Ali, Becher, Gabrielle, Murphy, Ruth, Wahie, Shyamal, Wright, Andrew, Griffiths, Christopher E.M., Reynolds, Nick J., Barker, Jonathan, Warren, Richard B., David Burden, A., Rispens, Theo, Standing, Joseph F., Smith, Catherine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070790/
https://www.ncbi.nlm.nih.gov/pubmed/31995663
http://dx.doi.org/10.1111/cts.12725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070790/
https://www.ncbi.nlm.nih.gov/pubmed/31995663
http://dx.doi.org/10.1111/cts.12725

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