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Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells

Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L. (Berberidaceae) plant. The results of cytotoxicity screening 48 h post-treatment showed that bersavine considerably inhibits the proliferation and viability of leukemic (Jurkat, MOLT-4), colon (HT-29), cervix...

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Detalles Bibliográficos
Autores principales: Koutova, Darja, Kulhava, Monika, Havelek, Radim, Majorosova, Martina, Královec, Karel, Habartova, Klara, Hošťálková, Anna, Opletal, Lubomír, Cahlikova, Lucie, Řezáčová, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071104/
https://www.ncbi.nlm.nih.gov/pubmed/32093423
http://dx.doi.org/10.3390/molecules25040964