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Telodendrimer-Based Macromolecular Drug Design using 1,3-Dipolar Cycloaddition for Applications in Biology

An architectural polymer containing hydrophobic isoxazole-based dendron and hydrophilic polyethylene glycol linear tail is prepared by a combination of the robust ZnCl(2) catalyzed alkyne-nitrile oxide 1,3-dipolar cycloaddition and esterification chemistry. This water soluble amphiphilic telodendrim...

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Detalles Bibliográficos
Autores principales: Yazdani, Hossein, Kaul, Esha, Bazgir, Ayoob, Maysinger, Dusica, Kakkar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071137/
https://www.ncbi.nlm.nih.gov/pubmed/32075239
http://dx.doi.org/10.3390/molecules25040857