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β-hydroxybutyrate Impedes the Progression of Alzheimer’s Disease and Atherosclerosis in ApoE-Deficient Mice

β-hydroxybutyrate (β-OHB) has been shown to exert an anti-inflammatory activity. Apolipoprotein-E (ApoE) is strongly associated with atherosclerosis and Alzheimer’s disease (AD). This study aimed to explore the therapeutic effect of β-OHB in the brain and the aorta of high-fat diet (HFD)-fed ApoE-de...

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Detalles Bibliográficos
Autores principales: Krishnan, Manigandan, Hwang, Jong Su, Kim, Mikyung, Kim, Yun Jin, Seo, Ji Hae, Jung, Jeeyoun, Ha, Eunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071244/
https://www.ncbi.nlm.nih.gov/pubmed/32069870
http://dx.doi.org/10.3390/nu12020471