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A Special Amino-Acid Formula Tailored to Boosting Cell Respiration Prevents Mitochondrial Dysfunction and Oxidative Stress Caused by Doxorubicin in Mouse Cardiomyocytes

Anthracycline anticancer drugs, such as doxorubicin (DOX), can induce cardiotoxicity supposed to be related to mitochondrial damage. We have recently demonstrated that a branched-chain amino acid (BCAA)-enriched mixture (BCAAem), supplemented with drinking water to middle-aged mice, was able to prom...

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Detalles Bibliográficos
Autores principales: Tedesco, Laura, Rossi, Fabio, Ragni, Maurizio, Ruocco, Chiara, Brunetti, Dario, Carruba, Michele O., Torrente, Yvan, Valerio, Alessandra, Nisoli, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071384/
https://www.ncbi.nlm.nih.gov/pubmed/31973180
http://dx.doi.org/10.3390/nu12020282