Targeting Mitochondrial Calcium Uptake with the Natural Flavonol Kaempferol, to Promote Metabolism/Secretion Coupling in Pancreatic β-cells

Pancreatic β-cells secrete insulin to lower blood glucose, following a meal. Maintenance of β-cell function is essential to preventing type 2 diabetes. In pancreatic β-cells, mitochondrial matrix calcium is an activating signal for insulin secretion. Recently, the molecular identity of the mitochond...

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Detalles Bibliográficos
Autores principales: Bermont, Flavien, Hermant, Aurelie, Benninga, Romy, Chabert, Christian, Jacot, Guillaume, Santo-Domingo, Jaime, Kraus, Marine R-C, Feige, Jerome N., De Marchi, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071504/
https://www.ncbi.nlm.nih.gov/pubmed/32093050
http://dx.doi.org/10.3390/nu12020538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071504/
https://www.ncbi.nlm.nih.gov/pubmed/32093050
http://dx.doi.org/10.3390/nu12020538

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