Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice

Epilepsy, characterized by recurrent seizures, affects 1% of the general population. Interestingly, 25% of diabetics develop seizures with a yet unknown mechanism. Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cultured astrocytes. Therefore, the present study aims...

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Detalles Bibliográficos
Autores principales: Méndez-González, Miguel P., Rivera-Aponte, David E., Benedikt, Jan, Maldonado-Martínez, Geronimo, Tejeda-Bayron, Flavia, Skatchkov, Serguei N., Eaton, Misty J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071513/
https://www.ncbi.nlm.nih.gov/pubmed/32019062
http://dx.doi.org/10.3390/brainsci10020072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071513/
https://www.ncbi.nlm.nih.gov/pubmed/32019062
http://dx.doi.org/10.3390/brainsci10020072

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