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Exercise Training Results in Lower Amyloid Plaque Load and Greater Cognitive Function in an Intensity Dependent Manner in the Tg2576 Mouse Model of Alzheimer’s Disease

Three months of exercise training (ET) decreases soluble Aβ(40) and Aβ(42) levels in an intensity dependent manner early in life in Tg2576 mice (Moore et al., 2016). Here, we examined the effects of 12 months of low- and high- intensity exercise training on cognitive function and amyloid plaque load...

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Detalles Bibliográficos
Autores principales: Thomas, Riya, Zimmerman, Scott D., Yuede, Kayla M., Cirrito, John R., Tai, Leon M., Timson, Benjamin F., Yuede, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071605/
https://www.ncbi.nlm.nih.gov/pubmed/32046299
http://dx.doi.org/10.3390/brainsci10020088