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Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia

During hypoxic conditions, cells undergo critical adaptive responses that include the up-regulation of hypoxia-inducible proteins (HIFs) and the induction of the unfolded protein response (UPR). While their induced signaling pathways have many distinct targets, there are some important connections a...

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Detalles Bibliográficos
Autores principales: Bartoszewska, Sylwia, Collawn, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071609/
https://www.ncbi.nlm.nih.gov/pubmed/32190062
http://dx.doi.org/10.1186/s11658-020-00212-1