A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3—PBX1 and β-catenin—ABCG2 signaling

BACKGROUND: The underlying mechanism involved in ovarian cancer stemness and chemoresistance remains largely unknown. Here, we explored whether the regulation of c-Kit and plasma membrane prohibitin (PHB) affects ovarian cancer stemness and chemotherapy resistance. METHODS: Mass spectrum analysis an...

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Detalles Bibliográficos
Autores principales: Fang, Chia-Hsun, Lin, Yi-Te, Liang, Chi-Ming, Liang, Shu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071647/
https://www.ncbi.nlm.nih.gov/pubmed/32169072
http://dx.doi.org/10.1186/s12929-020-00638-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071647/
https://www.ncbi.nlm.nih.gov/pubmed/32169072
http://dx.doi.org/10.1186/s12929-020-00638-x

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