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Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord
BACKGROUND: Spinal cord microglia plays a crucial role in the pathogenesis of neuropathic pain. However, the mechanisms underlying spinal microglial activation during neuropathic pain remain incompletely determined. Here, we investigated the role of Pellino1 (Peli1) and its interplay with spinal mic...
Autores principales: | Wang, Lijuan, Yin, Cui, Liu, Tianya, Abdul, Mannan, Zhou, Yan, Cao, Jun-Li, Lu, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071701/ https://www.ncbi.nlm.nih.gov/pubmed/32171293 http://dx.doi.org/10.1186/s12974-020-01754-z |
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