Review on the Structures and Activities of Transthyretin Amyloidogenesis Inhibitors

Transthyretin (TTR) is a tetrameric protein, and its dissociation, aggregation, deposition, and misfolding are linked to several human amyloid diseases. As the main transporter for thyroxine (T4) in plasma and cerebrospinal fluid, TTR contains two T4-binding sites, which are docked with T4 and subse...

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Detalles Bibliográficos
Autores principales: Guo, Xiaohua, Liu, Zhaowen, Zheng, Yizhou, Li, Yamei, Li, Linfu, Liu, Hai, Chen, Zhixi, Wu, Longhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071892/
https://www.ncbi.nlm.nih.gov/pubmed/32210536
http://dx.doi.org/10.2147/DDDT.S237252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071892/
https://www.ncbi.nlm.nih.gov/pubmed/32210536
http://dx.doi.org/10.2147/DDDT.S237252

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