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HIV-1 uncoats in the nucleus near sites of integration
HIV-1 capsid core disassembly (uncoating) must occur before integration of viral genomic DNA into the host chromosomes, yet remarkably, the timing and cellular location of uncoating is unknown. Previous studies have proposed that intact viral cores are too large to fit through nuclear pores and unco...
Autores principales: | Burdick, Ryan C., Li, Chenglei, Munshi, MohamedHusen, Rawson, Jonathan M. O., Nagashima, Kunio, Hu, Wei-Shau, Pathak, Vinay K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071919/ https://www.ncbi.nlm.nih.gov/pubmed/32094182 http://dx.doi.org/10.1073/pnas.1920631117 |
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