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Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?

PURPOSE OF REVIEW: Megalin is well known for its role in the reabsorption of proteins from the ultrafiltrate. Recent studies suggest that megalin also reabsorbs renin and angiotensinogen. Indeed, without megalin urinary renin and angiotensinogen levels massively increase, and even prorenin becomes d...

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Detalles Bibliográficos
Autores principales: Sun, Yuan, Lu, Xifeng, Danser, A. H. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072043/
https://www.ncbi.nlm.nih.gov/pubmed/32172431
http://dx.doi.org/10.1007/s11906-020-01037-1