Activation of Astroglial Connexin Is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine

Clozapine (CLZ) is a gold-standard antipsychotic against treatment-refractory schizophrenia, but is one of the most toxic antipsychotic agents. Pharmacological mechanisms of the double-edged sword clinical action of CLZ remain to be clarified. To explore the mechanisms of CLZ, the present study dete...

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Detalles Bibliográficos
Autores principales: Fukuyama, Kouji, Okubo, Ruri, Murata, Masahiko, Shiroyama, Takashi, Okada, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072131/
https://www.ncbi.nlm.nih.gov/pubmed/32054069
http://dx.doi.org/10.3390/cells9020414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072131/
https://www.ncbi.nlm.nih.gov/pubmed/32054069
http://dx.doi.org/10.3390/cells9020414

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