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Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells

Spontaneous senescence of cancer cells remains a puzzling and poorly understood phenomenon. Here we comprehensively characterize this process in primary epithelial ovarian cancer cells (pEOCs). Analysis of tumors from ovarian cancer patients showed an abundance of senescent cells in vivo. Further, s...

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Detalles Bibliográficos
Autores principales: Pakuła, Martyna, Mały, Ewa, Uruski, Paweł, Witucka, Anna, Bogucka, Małgorzata, Jaroszewska, Natalia, Makowska, Nicoletta, Niklas, Arkadiusz, Moszyński, Rafał, Sajdak, Stefan, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072138/
https://www.ncbi.nlm.nih.gov/pubmed/32012719
http://dx.doi.org/10.3390/cancers12020296