Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1

SMAD ubiquitination regulatory factor 1 (Smurf1) is a Nedd4 family E3 ubiquitin ligase that regulates cell motility, polarity and TGFβ signaling. Smurf1 contains an N-terminal protein kinase C conserved 2 (C2) domain that targets cell membranes and is required for interactions with membrane-localize...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Jordan L., Frick, Cary T., Johnson, Kristen A., Liu, Haining, Yong, Sylvia S., Varney, Allyson G., Wiest, Olaf, Stahelin, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072158/
https://www.ncbi.nlm.nih.gov/pubmed/32033048
http://dx.doi.org/10.3390/biom10020229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072158/
https://www.ncbi.nlm.nih.gov/pubmed/32033048
http://dx.doi.org/10.3390/biom10020229

Ejemplares similares