Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Amyloid-β (Aβ) peptides play a crucial role in the pathogenesis of Alzheimer’s disease (AD). Aβ production, aggregation, and clearance are thought to be important therapeutic targets for AD. Curcumin has been known to have an anti-amyloidogenic effect on AD. In the present study, we performed screen...

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Detalles Bibliográficos
Autores principales: Urano, Yasuomi, Takahachi, Mina, Higashiura, Ryo, Fujiwara, Hitomi, Funamoto, Satoru, Imai, So, Futai, Eugene, Okuda, Michiaki, Sugimoto, Hachiro, Noguchi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072163/
https://www.ncbi.nlm.nih.gov/pubmed/32028683
http://dx.doi.org/10.3390/cells9020349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072163/
https://www.ncbi.nlm.nih.gov/pubmed/32028683
http://dx.doi.org/10.3390/cells9020349

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