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Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation
Amyloid-β (Aβ) peptides play a crucial role in the pathogenesis of Alzheimer’s disease (AD). Aβ production, aggregation, and clearance are thought to be important therapeutic targets for AD. Curcumin has been known to have an anti-amyloidogenic effect on AD. In the present study, we performed screen...
Autores principales: | Urano, Yasuomi, Takahachi, Mina, Higashiura, Ryo, Fujiwara, Hitomi, Funamoto, Satoru, Imai, So, Futai, Eugene, Okuda, Michiaki, Sugimoto, Hachiro, Noguchi, Noriko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072163/ https://www.ncbi.nlm.nih.gov/pubmed/32028683 http://dx.doi.org/10.3390/cells9020349 |
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