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An Epitope on EGFR Loading Catastrophic Internalization Serve as a Novel Oncotarget for Hepatocellular Carcinoma Therapy

The precise role of Epidermal Growth Factor Receptor (EGFR) in Hepatocellular carcinoma (HCC) cells is unknown and EGFR inhibitors have not achieved positive clinical results. The rapid and drastic internalization of EGFR has been proved to successfully treat EGFR inhibitor-resistant patients in rec...

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Detalles Bibliográficos
Autores principales: Huang, Dianshuai, Fan, Qingjie, Liu, Zhiyi, Zhang, Shuqin, Huang, Wei, Li, Hongrui, Liang, Chongyang, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072198/
https://www.ncbi.nlm.nih.gov/pubmed/32079107
http://dx.doi.org/10.3390/cancers12020456