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An Epitope on EGFR Loading Catastrophic Internalization Serve as a Novel Oncotarget for Hepatocellular Carcinoma Therapy
The precise role of Epidermal Growth Factor Receptor (EGFR) in Hepatocellular carcinoma (HCC) cells is unknown and EGFR inhibitors have not achieved positive clinical results. The rapid and drastic internalization of EGFR has been proved to successfully treat EGFR inhibitor-resistant patients in rec...
Autores principales: | Huang, Dianshuai, Fan, Qingjie, Liu, Zhiyi, Zhang, Shuqin, Huang, Wei, Li, Hongrui, Liang, Chongyang, Sun, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072198/ https://www.ncbi.nlm.nih.gov/pubmed/32079107 http://dx.doi.org/10.3390/cancers12020456 |
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