Are Glucosylceramide-Related Sphingolipids Involved in the Increased Risk for Cancer in Gaucher Disease Patients? Review and Hypotheses

The roles of ceramide and its catabolites, i.e., sphingosine and sphingosine 1-phosphate, in the development of malignancies and the response to anticancer regimens have been extensively described. Moreover, an abundant literature points to the effects of glucosylceramide synthase, the mammalian enz...

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Detalles Bibliográficos
Autores principales: Dubot, Patricia, Astudillo, Leonardo, Therville, Nicole, Sabourdy, Frédérique, Stirnemann, Jérôme, Levade, Thierry, Andrieu-Abadie, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072201/
https://www.ncbi.nlm.nih.gov/pubmed/32085512
http://dx.doi.org/10.3390/cancers12020475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072201/
https://www.ncbi.nlm.nih.gov/pubmed/32085512
http://dx.doi.org/10.3390/cancers12020475

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