Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit

The microtubule-associated protein TPX2 is a key mitotic regulator that contributes through distinct pathways to spindle assembly. A well-characterised function of TPX2 is the activation, stabilisation and spindle localisation of the Aurora-A kinase. High levels of TPX2 are reported in tumours and t...

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Detalles Bibliográficos
Autores principales: Naso, Francesco D., Sterbini, Valentina, Crecca, Elena, Asteriti, Italia A., Russo, Alessandra D., Giubettini, Maria, Cundari, Enrico, Lindon, Catherine, Rosa, Alessandro, Guarguaglini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072206/
https://www.ncbi.nlm.nih.gov/pubmed/32041138
http://dx.doi.org/10.3390/cells9020374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072206/
https://www.ncbi.nlm.nih.gov/pubmed/32041138
http://dx.doi.org/10.3390/cells9020374

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