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Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit
The microtubule-associated protein TPX2 is a key mitotic regulator that contributes through distinct pathways to spindle assembly. A well-characterised function of TPX2 is the activation, stabilisation and spindle localisation of the Aurora-A kinase. High levels of TPX2 are reported in tumours and t...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072206/ https://www.ncbi.nlm.nih.gov/pubmed/32041138 http://dx.doi.org/10.3390/cells9020374 |