Tspan8-Tumor Extracellular Vesicle-Induced Endothelial Cell and Fibroblast Remodeling Relies on the Target Cell-Selective Response

Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment. TEX-promoted target reprogramming is still being disputed, we explored rat endothelial cell (EC) and lung fibroblas...

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Detalles Bibliográficos
Autores principales: Mu, Wei, Provaznik, Jan, Hackert, Thilo, Zöller, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072212/
https://www.ncbi.nlm.nih.gov/pubmed/32013145
http://dx.doi.org/10.3390/cells9020319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072212/
https://www.ncbi.nlm.nih.gov/pubmed/32013145
http://dx.doi.org/10.3390/cells9020319

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