Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age

Transcription of the ribosomal RNA genes (rDNA) that encode the three largest ribosomal RNAs (rRNA), is mediated by RNA Polymerase I (Pol I) and is a key regulatory step for ribosomal biogenesis. Although it has been reported over a century ago that the number and size of nucleoli, the site of ribos...

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Detalles Bibliográficos
Autores principales: Ferreira, Rita, Schneekloth, John S., Panov, Konstantin I., Hannan, Katherine M., Hannan, Ross D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072222/
https://www.ncbi.nlm.nih.gov/pubmed/31973211
http://dx.doi.org/10.3390/cells9020266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072222/
https://www.ncbi.nlm.nih.gov/pubmed/31973211
http://dx.doi.org/10.3390/cells9020266

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