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Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age

Transcription of the ribosomal RNA genes (rDNA) that encode the three largest ribosomal RNAs (rRNA), is mediated by RNA Polymerase I (Pol I) and is a key regulatory step for ribosomal biogenesis. Although it has been reported over a century ago that the number and size of nucleoli, the site of ribos...

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Detalles Bibliográficos
Autores principales:	Ferreira, Rita, Schneekloth, John S., Panov, Konstantin I., Hannan, Katherine M., Hannan, Ross D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072222/ https://www.ncbi.nlm.nih.gov/pubmed/31973211 http://dx.doi.org/10.3390/cells9020266

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