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Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies

The vast majority of mortality in breast cancer results from distant metastasis. Brain metastases occur in as many as 30% of patients with advanced breast cancer, and the 1-year survival rate of these patients is around 20%. Pre-clinical animal models that reliably reflect the biology of breast canc...

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Detalles Bibliográficos
Autores principales: Oshi, Masanori, Okano, Maiko, Maiti, Aparna, Rashid, Omar M., Saito, Katsuharu, Kono, Koji, Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072242/
https://www.ncbi.nlm.nih.gov/pubmed/32074948
http://dx.doi.org/10.3390/cancers12020444