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Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies
The vast majority of mortality in breast cancer results from distant metastasis. Brain metastases occur in as many as 30% of patients with advanced breast cancer, and the 1-year survival rate of these patients is around 20%. Pre-clinical animal models that reliably reflect the biology of breast canc...
Autores principales: | Oshi, Masanori, Okano, Maiko, Maiti, Aparna, Rashid, Omar M., Saito, Katsuharu, Kono, Koji, Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072242/ https://www.ncbi.nlm.nih.gov/pubmed/32074948 http://dx.doi.org/10.3390/cancers12020444 |
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