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Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation

Background: Contextual fear conditioning (CFC) is a rodent model that induces a high and long-lasting level of conditioning associated with traumatic memory formation; this behavioral paradigm resembles many characteristics of posttraumatic stress disorder (PSTD). Chemokines (chemotactic cytokines)...

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Detalles Bibliográficos
Autores principales: Merino, José Joaquín, Muñetón-Gomez, Vilma, Muñetón-Gómez, César, Pérez-Izquierdo, María Ángeles, Loscertales, María, Toledano Gasca, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072246/
https://www.ncbi.nlm.nih.gov/pubmed/32024104
http://dx.doi.org/10.3390/biom10020212