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Secreted Phospholipase A(2)-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation–Fibrosis Link

Secreted phospholipase A(2)-IIA (sPLA(2)-IIA) is a pro-inflammatory protein associated with cardiovascular disorders, whose functions and underlying mechanisms in cardiac remodelling are still under investigation. We herein study the role of sPLA(2)-IIA in cardiac fibroblast (CFs)-to-myofibroblast d...

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Detalles Bibliográficos
Autores principales: Martin, Ruben, Gutierrez, Beatriz, Cordova, Claudia, San Roman, Alberto, Alvarez, Yolanda, Hernandez, Marita, Cachofeiro, Victoria, Nieto, Maria L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072256/
https://www.ncbi.nlm.nih.gov/pubmed/32046347
http://dx.doi.org/10.3390/cells9020396