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WNT5A-Induced Activation of the Protein Kinase C Substrate MARCKS Is Required for Melanoma Cell Invasion

WNT5A is a well-known mediator of melanoma cell invasion and metastasis via its ability to activate protein kinase C (PKC), which is monitored by phosphorylation of the endogenous PKC substrate myristoylated alanine-rich c-kinase substrate (MARCKS). However, a possible direct contribution of MARCKS...

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Detalles Bibliográficos
Autores principales: Mohapatra, Purusottam, Yadav, Vikas, Toftdahl, Maren, Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072258/
https://www.ncbi.nlm.nih.gov/pubmed/32033033
http://dx.doi.org/10.3390/cancers12020346