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Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

Purpose: To investigate whether and how leukemia inhibitory factor (Lif) is involved in mediating the neuroprotective effects of Norrin on retinal ganglion cells (RGC) following excitotoxic damage. Norrin is a secreted protein that protects RGC from N-methyl-d-aspartate (NMDA)-mediated excitotoxic d...

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Detalles Bibliográficos
Autores principales: Kassumeh, Stefan, Leopold, Stephanie, Fuchshofer, Rudolf, Thomas, Carina N., Priglinger, Siegfried G., Tamm, Ernst R., Ohlmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072268/
https://www.ncbi.nlm.nih.gov/pubmed/31979254
http://dx.doi.org/10.3390/cells9020277