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p53’s Extended Reach: The Mutant p53 Secretome

p53 suppresses tumorigenesis by activating a plethora of effector pathways. While most of these operate primarily inside of cells to limit proliferation and survival of incipient cancer cells, many extend to the extracellular space. In particular, p53 controls expression and secretion of numerous ex...

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Detalles Bibliográficos
Autores principales: Pavlakis, Evangelos, Stiewe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072272/
https://www.ncbi.nlm.nih.gov/pubmed/32075247
http://dx.doi.org/10.3390/biom10020307