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Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis

Extracorporeal photopheresis (ECP), a modality that exposes isolated leukocytes to the photosensitizer 8-methoxypsoralen (8-MOP) and ultraviolet-A (UV-A) light, is used to treat conditions such as cutaneous T-cell lymphoma and graft-versus-host disease. However, the current procedure of ECP has limi...

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Detalles Bibliográficos
Autores principales: Darvekar, Sagar, Juzenas, Petras, Oksvold, Morten, Kleinauskas, Andrius, Holien, Toril, Christensen, Eidi, Stokke, Trond, Sioud, Mouldy, Peng, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072277/
https://www.ncbi.nlm.nih.gov/pubmed/32041351
http://dx.doi.org/10.3390/cancers12020377