TDP1 and TOP1 Modulation in Olaparib-Resistant Cancer Determines the Efficacy of Subsequent Chemotherapy

The aim of this study was to elucidate the carryover effect of olaparib to subsequent chemotherapy and its underlying mechanisms. We generated olaparib-resistant SNU-484, SNU-601, SNU-668, and KATO-III gastric cancer cell lines and confirmed their resistance by cell viability and colony forming assa...

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Detalles Bibliográficos
Autores principales: Kim, Jin Won, Min, Ahrum, Im, Seock-Ah, Jang, Hyemin, Kim, Yu Jin, Kim, Hee-Jun, Lee, Kyung-Hun, Kim, Tae-Yong, Lee, Keun Wook, Oh, Do-Youn, Kim, Jee-Hyun, Bang, Yung-Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072281/
https://www.ncbi.nlm.nih.gov/pubmed/32028591
http://dx.doi.org/10.3390/cancers12020334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072281/
https://www.ncbi.nlm.nih.gov/pubmed/32028591
http://dx.doi.org/10.3390/cancers12020334

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