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Targeting CD47 as a Novel Immunotherapy for Multiple Myeloma

Multiple myeloma (MM) remains to be incurable despite recent therapeutic advances. CD47, an immune checkpoint known as the “don’t eat me” signal, is highly expressed on the surface of various cancers, allowing cancer cells to send inhibitory signals to macrophages and impede phagocytosis and immune...

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Detalles Bibliográficos
Autores principales: Sun, Jennifer, Muz, Barbara, Alhallak, Kinan, Markovic, Matea, Gurley, Shannon, Wang, Zhe, Guenthner, Nicole, Wasden, Katherine, Fiala, Mark, King, Justin, Kohnen, Daniel, Salama, Noha Nabil, Vij, Ravi, Azab, Abdel Kareem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072283/
https://www.ncbi.nlm.nih.gov/pubmed/32012878
http://dx.doi.org/10.3390/cancers12020305