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How Quickly Do Proteins Fold and Unfold, and What Structural Parameters Correlate with These Values?

The correlations between the logarithm of the unfolding rate of 108 proteins and their structural parameters were calculated. We showed that there is a good correlation between the logarithm of folding and unfolding rates (0.79) and protein stability and unfolding rate (0.79). Thus, the faster the p...

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Detalles Bibliográficos
Autores principales: Glyakina, Anna V., Galzitskaya, Oxana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072309/
https://www.ncbi.nlm.nih.gov/pubmed/32013136
http://dx.doi.org/10.3390/biom10020197