Silencing of PARP2 Blocks Autophagic Degradation

Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD(+). PARP1 and PARP10 were previously implicated in the regulation of autophagy. Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA. The cytosolic el...

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Detalles Bibliográficos
Autores principales: Jankó, Laura, Sári, Zsanett, Kovács, Tünde, Kis, Gréta, Szántó, Magdolna, Antal, Miklós, Juhász, Gábor, Bai, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072353/
https://www.ncbi.nlm.nih.gov/pubmed/32046043
http://dx.doi.org/10.3390/cells9020380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072353/
https://www.ncbi.nlm.nih.gov/pubmed/32046043
http://dx.doi.org/10.3390/cells9020380

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