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Silencing of PARP2 Blocks Autophagic Degradation
Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD(+). PARP1 and PARP10 were previously implicated in the regulation of autophagy. Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA. The cytosolic el...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072353/ https://www.ncbi.nlm.nih.gov/pubmed/32046043 http://dx.doi.org/10.3390/cells9020380 |